An Expedient Synthesis of the Repeating Unit of the Acidic Polysaccharide of the Bacteriolytic Complex of Lysoamidase
- 21 December 2004
- journal article
- research article
- Published by Wiley in Chemistry – A European Journal
- Vol. 11 (3), 1010-1016
- https://doi.org/10.1002/chem.200400862
Abstract
The first synthesis of the trisaccharide repeating unit of the acidic polysaccharide of the bacteriolytic complex of lysoamidase is presented. The construction is based on a linear glycosylation strategy that starts from the reducing end and employs thio‐ and selenoglycosides in a highly stereoselective manner by a single set of activation conditions. The thus‐formed trisaccharide is selectively deprotected and oxidised, after which a final deprotection step furnishes the desired repeating unit.Keywords
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