A Handling Study to Assess Use of the Respimat® Soft Mist™ Inhaler in Children Under 5 Years Old
Open Access
- 1 October 2015
- journal article
- research article
- Published by Mary Ann Liebert Inc in Journal of Aerosol Medicine and Pulmonary Drug Delivery
- Vol. 28 (5), 372-381
- https://doi.org/10.1089/jamp.2014.1159
Abstract
Background: Respimat® Soft Mist™ Inhaler (SMI) is a hand-held device that generates an aerosol with a high, fine-particle fraction, enabling efficient lung deposition. The study objective was to assess inhalation success among children using Respimat SMI, and the requirement for assistance by the parent/caregiver and/or a valved holding chamber (VHC). Methods: This open-label study enrolled patients aged Results: Of the children aged 4 to n=27) and 3 to n=30), 55.6% and 30.0%, respectively, achieved success without a VHC or help; with assistance, another 29.6% and 10.0%, respectively, achieved success, and the remaining children were successful with VHC. All children aged 2 to n=20) achieved success with the Respimat SMI and VHC. Of those aged n=22), 95.5% had successful handling of the Respimat SMI with VHC and parent/caregiver help. Inhalation flow profiles generally confirmed the outcome of the handling assessment by the investigators. Most parent/caregiver and/or child respondents were satisfied with operation, instructions for use, handling, and ease of holding the Respimat SMI with or without a VHC. Conclusions: The Respimat SMI is suitable for children aged <5 years; however, children aged <5 years are advised to add a VHC to complement its use.Keywords
This publication has 21 references indexed in Scilit:
- Development of Respimat® Soft Mist™ Inhaler and its clinical utility in respiratory disordersMedical Devices: Evidence and Research, 2011
- Guidelines for aerosol devices in infants, children and adults: which to choose, why and how to achieve effective aerosol therapyExpert Review of Respiratory Medicine, 2011
- Patient preferences for inhaler devices in chronic obstructive pulmonary disease: experience with Respimat® Soft Mist™ InhalerInternational Journal of Chronic Obstructive Pulmonary Disease, 2009
- Does Parental Involvement in Pediatric Emergency Department Asthma Treatment Affect Home Management?Journal of Asthma, 2009
- Device Selection and Outcomes of Aerosol Therapy: Evidence-Based GuidelinesChest, 2005
- Respimat?? Soft Mist??? Inhaler versus Hydrofluoroalkane Metered Dose InhalerTreatments in Respiratory Medicine, 2005
- Reduced Peak Inspiratory Effort through the Diskus?? and the Turbuhaler?? due to Mishandling is??Common in Clinical PracticeClinical Drug Investigation, 2005
- Efficacy and safety of ipratropium bromide plus fenoterol inhaled via Respimat® Soft Mist™ Inhaler vs. a conventional metered dose inhaler plus spacer in children with asthmaPediatric Pulmonology, 2004
- A Mathematical Model of Aerosol Holding ChambersJournal of Aerosol Medicine, 1999
- Errors in Inhalation Technique and Efficiency in Inhaler Use in Asthmatic ChildrenAllergy, 1986