Rotarix: Development of a Live Attenuated Monovalent Human Rotavirus Vaccine
- 1 January 2006
- journal article
- Published by SLACK, Inc. in Pediatric Annals
- Vol. 35 (1), 38-43
- https://doi.org/10.3928/0090-4481-20060101-12
Abstract
Pediatric Annals | The public health burden of rotavirus disease, reviewed in the article by Zahn and Marshall (see page 23), provides sufficient justification for the development of a rotavirus vaccine. Despite the withdrawal of one vaccine in the United States, rhesus rotavirus vaccine tetravalent (RRV-TV, RotaShield), other rotavirus vaccines should be available shortly. This article reviews the background,This publication has 39 references indexed in Scilit:
- Evaluation of RIX4414, A Live, Attenuated Rotavirus Vaccine, in a Randomized, Double‐Blind, Placebo‐Controlled Phase 2 Trial Involving 2464 Singaporean InfantsThe Journal of Infectious Diseases, 2005
- Memory T-Cell Response to Rotavirus Detected with a Gamma Interferon Enzyme-Linked Immunospot AssayJournal of Virology, 2005
- A Rotavirus Vaccine for Prophylaxis of Infants Against Rotavirus GastroenteritisThe Pediatric Infectious Disease Journal, 2004
- Safety and immunogenicity of RIX4414 live attenuated human rotavirus vaccine in adults, toddlers and previously uninfected infantsVaccine, 2004
- Possible Mechanisms of Protection Elicited by Candidate Rotavirus Vaccines as Determined with the Adult Mouse ModelViral Immunology, 2003
- Second‐Year Follow‐up Evaluation of Live, Attenuated Human Rotavirus Vaccine 89‐12 in Healthy InfantsThe Journal of Infectious Diseases, 2002
- Evidence that Protection against Rotavirus Diarrhea after Natural Infection Is Not Dependent on Serotype-Specific Neutralizing AntibodyThe Journal of Infectious Diseases, 1992
- Field Trial of Rhesus Rotavirus or Human-Rhesus Rotavirus Reassortant Vaccine of VP7 Serotype 3 or 1 Specificity in InfantsThe Journal of Infectious Diseases, 1992
- Clinical efficacy of the RIT 4237 live attenuated bovine rotavirus vaccine in infants vaccinated before a rotavirus epidemicThe Journal of Pediatrics, 1985
- Clinical Immunity after Neonatal Rotavirus InfectionNew England Journal of Medicine, 1983