Effect of prostaglandins and dibutyryl cyclic AMP on the morphology of cells in primary astroglial cultures and on metabolic enzymes of GABA and glutamate metabolism
- 1 January 1981
- journal article
- Published by Springer Science and Business Media LLC in Cellular and Molecular Life Sciences
- Vol. 37 (1), 19-21
- https://doi.org/10.1007/bf01965545
Abstract
Prostaglandins (PGE1) and dibutyryl cyclic AMP (dBc AMP) induce similar morphological changes in astrocytes obtained in primary cultures. PGE1 and dBc AMP increased 2 enzymes of GABA and glutamate metabolism, GABA-T and AAT, but did not modify GDH and GLN-S. Prostaglandins probably affect the cAMP content of glial cells and act in the same way as dBc AMP on glial cell differentiation.Keywords
This publication has 8 references indexed in Scilit:
- GABA metabolism in cultured glial cellsNeurochemical Research, 1979
- GABA Metabolism in Cultured Glial CellsPublished by Springer Science and Business Media LLC ,1979
- Glial fibrillary acidic protein in primary astroglial cell cultures derived from newborn rat brainFEBS Letters, 1977
- TRACER KINETIC MODEL ANALYSIS OF POTASSIUM UPTAKE BY DISSOCIATED NERVE CELL CULTURES: GLIAL‐NEURONAL INTERRELATIONSHIPJournal of Neurochemistry, 1974
- Méthode radio-isotopique rapide de mesure de l'activité 4-aminobutyrate: 2-oxoglutarate aminotransferase (GABA-transaminase)Biochimie, 1973
- Morphological Differentiation induced by Prostaglandin in Mouse Neuroblastoma Cells in CultureNature New Biology, 1972
- Glutamine Synthetase. Determination of Its Distribution in Brain during Development*Biochemistry, 1966
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951