Effects of chitosan—a coagulating agent for food processing wastes—in the diets of rats on growth and liver and blood composition
- 1 May 1976
- journal article
- Published by Springer Science and Business Media LLC in Bulletin of Environmental Contamination and Toxicology
- Vol. 15 (5), 555-563
- https://doi.org/10.1007/bf01685704
Abstract
Effects of feeding free chitosan to rats at graded levels up to 15 percent of the diet for eight weeks was investigated. Animals receiving diets containing 5 percent or less of chitosan grew well at comparable rates. Progressive growth reductions occurred when chitosan was increased to 10 and 15 percent of the diet and enlargement of liver and kidneys was observed only in animals receiving the highest level of dietary chitosan. Liver moisture, protein, lipid, ash, and nucleic acids; blood hemoglobin and packed cell volume; and serum total protein, albumin, ceruloplasmin and transferrin were determined. Values for these components of liver and blood were altered significantly in the animals receiving the highest level of chitosan when compared to control animals. However, in animals receiving 5 percent or less of dietary chitosan none of these measures of tissue composition was different from controls, except for liver protein concentration of rats fed the 5 percent of chitosan diet. Animal feeds containing coagulated by-products are not expected to contain over 0.2% chitosan in the total diet. No adverse effects have been observed at this level in rat feeding studies. Therefore the tolerance level for dietary chitosan appears to be well above the levels expected to be in animal feeds containing by-products recovered from food processing wastes by coagulation with chitosan.Keywords
This publication has 14 references indexed in Scilit:
- Coagulation with Chitosan—An Aid to Recovery of By-Products from Egg Breaking WastesPoultry Science, 1975
- Use of Chitosan for the Reduction and Recovery of Solids in Poultry Processing Waste EffluentsPoultry Science, 1975
- REDUCTION OF SUSPENDED SOLIDS IN VEGETABLE CANNING WASTE EFFLUENTS BY COAGULATION WITH CHITOSANJournal of Food Science, 1975
- Measurement of Human Serum Ceruloplasmin by Its p-Phenylenediamine Oxidase ActivityClinical Chemistry, 1970
- Ferrozine---a new spectrophotometric reagent for ironAnalytical Chemistry, 1970
- Direct Measurement of Serum Iron and Binding CapacityClinical Chemistry, 1966
- The Determination of Nucleic AcidsMethods of biochemical analysis, 1966
- Multiple Range and Multiple F TestsBiometrics, 1955
- A MICROCHEMICAL DETERMINATION OF DESOXYRIBONUCLEIC ACIDJournal of Biological Chemistry, 1952
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951