The Relationship Between Serum Lipid Profile and Selected Trace Elements for Adult Men in Mosul City
Open Access
- 16 July 2012
- journal article
- Published by Oman Medical Journal in Oman Medical Journal
- Vol. 27 (4), 300-303
- https://doi.org/10.5001/omj.2012.74
Abstract
To evaluate the correlations of the serum concentrations of copper, zinc, and manganese with lipid profile parameters of adult men in Mosul City, Iraq. The study included 51 apparently healthy adult men as a control group aged 34-62 years (group 1), and 31 hyperlipidemic patients aged 37-60 years (group 2). Trace elements copper, zinc and manganese were determined using atomic absorption spectrometry. Concentrations of total cholesterol, triglyceride and high density lipoprotein cholesterol were determined using enzymatic method. Indirect serum concentration of low-density lipoprotein cholesterol were calculated via the Friedewald formula. Data were evaluated as mean and standard deviation by analysis of variance (ANOVA) and t-test. The results indicated that there is a significant lower level of serum zinc in hyperlipidemic patients compared with the control group, while copper and manganese showed no significant differences between the two groups. A significant negative correlation was found between serum zinc and total cholesterol, low-density lipoprotein cholesterol, triglyceride and low/high-density lipoprotein cholesterol ratio; while a significant positive correlation was found between serum zinc and high density lipoprotein cholesterol. In addition, a significant positive correlation between copper and triglyceride existed in the patient group, while the control group showed no such correlation. Hyperlipidemia may possibly be related to a decrease in the level of serum zinc in hyperlipidemic adult men. The data also supports the concept that zinc supplementation might be useful in improving metabolic complications in subjects with hyperlipidemia.Keywords
This publication has 19 references indexed in Scilit:
- Dietary Intake and Serum and Hair Concentrations of Minerals and their Relationship with Serum Lipids and Glucose Levels in Hypertensive and Obese Patients with Insulin ResistanceBiological Trace Element Research, 2010
- Cardiovascular Disease and Risk Factors in AsiaCirculation, 2008
- Lipid profile of adult Nepalese population.2008
- Effect of smoking on lipid profile and lipid peroxidation in normal subjects.2006
- Effect of starvation stress on lipid peroxidation and lipid profile in rabbits.2002
- High-Energy Diets, Fatty Acids and Endothelial Cell Function: Implications for AtherosclerosisJournal of the American College of Nutrition, 2001
- The Relationship Between Zinc and Copper Status and Lipid Levels in African-AmericansBiological Trace Element Research, 2001
- Role of zinc in lipid and fatty acid metabolism and in membranes.1988
- Relationship between the nutritional status of zinc and cholesterol concentration of serum lipoproteins in adult male ratsThe American Journal of Clinical Nutrition, 1981
- Influence of dietary copper and zinc on rat lipid metabolismJournal of Agricultural and Food Chemistry, 1977