Frequent Arousal from Hibernation Linked to Severity of Infection and Mortality in Bats with White-Nose Syndrome
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Open Access
- 20 June 2012
- journal article
- biology
- Published by Public Library of Science (PLoS) in PLOS ONE
- Vol. 7 (6), e38920
- https://doi.org/10.1371/journal.pone.0038920
Abstract
White-nose syndrome (WNS), an emerging infectious disease that has killed over 5.5 million hibernating bats, is named for the causative agent, a white fungus (Geomyces destructans (Gd)) that invades the skin of torpid bats. During hibernation, arousals to warm (euthermic) body temperatures are normal but deplete fat stores. Temperature-sensitive dataloggers were attached to the backs of 504 free-ranging little brown bats (Myotis lucifugus) in hibernacula located throughout the northeastern USA. Dataloggers were retrieved at the end of the hibernation season and complete profiles of skin temperature data were available from 83 bats, which were categorized as: (1) unaffected, (2) WNS-affected but alive at time of datalogger removal, or (3) WNS-affected but found dead at time of datalogger removal. Histological confirmation of WNS severity (as indexed by degree of fungal infection) as well as confirmation of presence/absence of DNA from Gd by PCR was determined for 26 animals. We demonstrated that WNS-affected bats aroused to euthermic body temperatures more frequently than unaffected bats, likely contributing to subsequent mortality. Within the subset of WNS-affected bats that were found dead at the time of datalogger removal, the number of arousal bouts since datalogger attachment significantly predicted date of death. Additionally, the severity of cutaneous Gd infection correlated with the number of arousal episodes from torpor during hibernation. Thus, increased frequency of arousal from torpor likely contributes to WNS-associated mortality, but the question of how Gd infection induces increased arousals remains unanswered.Keywords
This publication has 31 references indexed in Scilit:
- Inoculation of bats with European Geomyces destructans supports the novel pathogen hypothesis for the origin of white-nose syndromeProceedings of the National Academy of Sciences of the United States of America, 2012
- Changes in Body Condition of Hibernating Bats Support the Thrifty Female Hypothesis and Predict Consequences for Populations with White-Nose SyndromePLOS ONE, 2011
- Pan-European Distribution of White-Nose Syndrome Fungus (Geomyces destructans) Not Associated with Mass MortalityPLOS ONE, 2011
- Wing pathology of white-nose syndrome in bats suggests life-threatening disruption of physiologyBMC Biology, 2010
- Increasing Incidence of Geomyces destructans Fungus in Bats from the Czech Republic and SlovakiaPLOS ONE, 2010
- Hibernation: the immune system at rest?Journal of Leukocyte Biology, 2010
- Could localized warm areas inside cold caves reduce mortality of hibernating bats affected by white‐nose syndrome?Frontiers in Ecology and the Environment, 2009
- AROUSAL PATTERNS, METABOLIC RATE, AND AN ENERGY BUDGET OF EASTERN RED BATS (LASIURUS BOREALIS) IN WINTERJournal of Mammalogy, 2006
- Hibernation patterns in mammals: a role for bacterial growth?Functional Ecology, 2006
- Analyzing Tables of Statistical TestsEvolution, 1989