Puberty in Laron type dwarfism

Abstract

The onset and progress of puberty was followed in 18 patients (7 males and 11 females) with Laron-type dwarfism (LTD). The boys had delayed puberty, testicular enlargement occurring between 12–14 years being the first sign. The first conscious ejaculation occurred between 17–21 years and full maturity was reached after the age of 22. In girls menarche occurred between 13–14 years and full maturity was reached between 16–19 years. Two patients—one male and one female—have children.