Intrinsic Asthma in Adults
- 6 December 1976
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 236 (23), 2626-2628
- https://doi.org/10.1001/jama.1976.03270240022017
Abstract
Of 28 patients with severe asthma routinely examined with upper gastrointestinal (UGI) x-ray films, 18 (64%) were found to have hiatus hernia and 13 (46%) were found to have demonstrable gastroesophageal reflux. These prevalences differed significantly (P<.001) from those seen in a control population (19% and 5%, respectively). These data suggest that aspiration of gastric acid is a frequent incitant to severe asthma and that it should be routinely sought in the treatment-resisant asthmatic patient. Intensive medical regimens directed against reflux and acidity may bring notable improvement in asthma symptoms. Surgical restoration of effective lower esophageal sphincter function has proved to be curative in other reported studies. (JAMA236:2626-2628, 1976)Keywords
This publication has 2 references indexed in Scilit:
- Esophageal Reflux as a Trigger in AsthmaDiseases of the Chest, 1966
- “Silent” Gastroesophageal Reflux: An Important but Little Known Cause of Pulmonary ComplicationsDiseases of the Chest, 1962