To carry out functioning and dynamic vegetation studies, a temporal analysis is needed. So far, only data provided by the National Oceanic and Atmospheric Administration (NOAA) satellites with Advanced Very High Resolution Radiometer (AVHRR) sensors offer the required temporal resolution, but their spatial resolution is coarse (1.1 km). But, in many situations, the vegetation cover is heterogeneous and the 1.1 km AVHRR pixel contains several types of land use radiometrically different and is, in fact, a mixed pixel. Thus, the reflectance and consequently deduced parameters (NDVI, LAI, etc.) measured by AVHRR is actually average value and does not represent a value for each vegetation class present in the pixel. The objective is to extract the reflectance of each vegetation class from the mixed pixel using NOAA-AVHRR data and SPOT-HRV data simultaneously which give the proportions of each type of vegetation inside the mixed pixel through a classification map. The paper presents a method for radiometrically unmixing coarse resolution signals through the inversion of linear mixture modelling on heterogeneous regions of natural vegetation (Bidi-Bahn) in Burkina-Faso and in Niger (Hapex site). In a first step, simulated coarse resolution data (NOAA-AVHRR) obtained from the degradation of SPOT images are used to assess the method. In a second step, real NOAA-AVHRR data are used and some elements of validation are given by comparing the results to airborne reflectance measurements.