Chromatin assembly by DNA-translocating motors
- 1 August 2003
- journal article
- review article
- Published by Springer Science and Business Media LLC in Nature Reviews Molecular Cell Biology
- Vol. 4 (8), 613-620
- https://doi.org/10.1038/nrm1177
Abstract
Chromatin assembly is required for the duplication of eukaryotic chromosomes and functions at the interface between cell-cycle progression and gene expression. The central machinery that mediates chromatin assembly consists of histone chaperones, which deliver histones to the DNA, and ATP-utilizing motor proteins, which are DNA-translocating factors that act in conjunction with the histone chaperones to mediate the deposition of histones into periodic nucleosome arrays. Here, we describe these factors and propose possible mechanisms by which DNA-translocating motors might catalyse chromatin assembly.Keywords
This publication has 100 references indexed in Scilit:
- An ACF1–ISWI chromatin-remodeling complex is required for DNA replication through heterochromatinNature Genetics, 2002
- Strand pairing by Rad54 and Rad51 is enhanced by chromatinGenes & Development, 2002
- TRF2 associates with DREF and directs promoter-selective gene expression in DrosophilaNature, 2002
- The in vivo functions of ATP-dependent chromatin-remodelling factorsNature Reviews Molecular Cell Biology, 2002
- Translating the Histone CodeScience, 2001
- Higher-order folding of heterochromatin: Protein bridges span the nucleosome arraysBiochemistry and Cell Biology, 2001
- Purification and Characterization of a Human Factor That Assembles and Remodels ChromatinPublished by Elsevier BV ,2000
- NAP-2: histone chaperone function and phosphorylation state through the cell cycleJournal of Molecular Biology, 2000
- Nuclear chaperonesSeminars in Cell & Developmental Biology, 2000
- Chromatin assembly in Xenopus oocytes: In vitro studiesCell, 1984