Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial
Top Cited Papers
- 1 June 2020
- journal article
- research article
- Published by Elsevier BV in The Lancet
- Vol. 395 (10240), 1845-1854
- https://doi.org/10.1016/s0140-6736(20)31208-3
Abstract
No abstract availableKeywords
This publication has 28 references indexed in Scilit:
- A two-dose heterologous prime-boost vaccine regimen eliciting sustained immune responses to Ebola Zaire could support a preventive strategy for future outbreaksHuman Vaccines & Immunotherapeutics, 2016
- A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVAThe New England Journal of Medicine, 2016
- Immunodominant SARS Coronavirus Epitopes in Humans Elicited both Enhancing and Neutralizing Effects on Infection in Non-human PrimatesACS Infectious Diseases, 2016
- Safety and immunogenicity of a chimpanzee adenovirus-vectored Ebola vaccine in healthy adults: a randomised, double-blind, placebo-controlled, dose-finding, phase 1/2a studyThe Lancet Infectious Diseases, 2015
- Safety and immunogenicity of a novel recombinant adenovirus type-5 vector-based Ebola vaccine in healthy adults in China: preliminary report of a randomised, double-blind, placebo-controlled, phase 1 trialThe Lancet, 2015
- Virus-Specific Memory CD8 T Cells Provide Substantial Protection from Lethal Severe Acute Respiratory Syndrome Coronavirus InfectionJournal of Virology, 2014
- Recombinant adenovirus type 5 HIV gag/pol/nef vaccine in South Africa: unblinded, long-term follow-up of the phase 2b HVTN 503/Phambili studyThe Lancet Infectious Diseases, 2014
- T Cell Responses Are Required for Protection from Clinical Disease and for Virus Clearance in Severe Acute Respiratory Syndrome Coronavirus-Infected MiceJournal of Virology, 2010
- A human SARS-CoV neutralizing antibody against epitope on S2 proteinBiochemical and Biophysical Research Communications, 2005
- Quantifying Adenovirus-Neutralizing Antibodies by Luciferase Transgene Detection: Addressing Preexisting Immunity to Vaccine and Gene Therapy VectorsJournal of Clinical Microbiology, 2003