Capnocytophaga canimorsus endocarditis
Open Access
- 1 March 2004
- journal article
- review article
- Published by Microbiology Society in Journal of Medical Microbiology
- Vol. 53 (3), 245-248
- https://doi.org/10.1099/jmm.0.05274-0
Abstract
Capnocytophaga canimorsus is a fastidious, Gram-negative rod that forms part of the normal oral flora of dogs and cats. Known for its ability to cause fulminant sepsis following dog bites, particularly in asplenic patients or alcoholics, this bacterium is also an uncommon cause of endocarditis. This article reviews 12 cases of endocarditis caused by C. canimorsus. Mean age of patients was 53 years, with 78 % of cases occurring in males. Overall, a history of dog-bite was documented in four cases (33 %) and a further four (33 %) reported contact with dogs. Four (33 %) of the endocarditis cases had underlying cardiological risk factors and two abused alcohol, but none had had a previous splenectomy. Subacute presentation, often involving more than one hospital admission, was common, as were initially negative blood cultures. A variety of antibiotics was used, but penicillins were the most common therapy. Three (25 %) of the 12 endocarditis patients died.Keywords
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