A pilot study of IL-1 inhibition by anakinra in acute gout
Open Access
- 12 March 2007
- journal article
- case report
- Published by Springer Science and Business Media LLC in Arthritis Research & Therapy
- Vol. 9 (2), R28
- https://doi.org/10.1186/ar2143
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- Cryopyrin activates the inflammasome in response to toxins and ATPNature, 2006
- Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3Nature, 2006
- Gout-associated uric acid crystals activate the NALP3 inflammasomeNature, 2006
- Epidemiology, risk factors, and lifestyle modifications for goutArthritis Research & Therapy, 2006
- Innate immunity conferred by toll‐like receptors 2 and 4 and myeloid differentiation factor 88 expression is pivotal to monosodium urate monohydrate crystal–induced inflammationArthritis & Rheumatism, 2005
- NLRs join TLRs as innate sensors of pathogensTrends in Immunology, 2005
- Inflammatory Caspases: Linking an Intracellular Innate Immune System to Autoinflammatory DiseasesCell, 2004
- Urate crystals stimulate production of tumor necrosis factor alpha from human blood monocytes and synovial cells. Cytokine mRNA and protein kinetics, and cellular distribution.JCI Insight, 1991
- Interleukin 1 (IL 1) as a mediator of crystal arthritis. Stimulation of T cell and synovial fibroblast mitogenesis by urate crystal-induced IL 1.The Journal of Immunology, 1987
- Crystal‐induced endogenous pyrogen production. A further look at gouty inflammationArthritis & Rheumatism, 1985