Carrier-mediated processes at several rat brain interfaces determine the neuropharmacokinetics of morphine and morphine-6-β-d-glucuronide
- 11 April 2006
- journal article
- Published by Elsevier BV in Life Sciences
- Vol. 78 (20), 2302-2314
- https://doi.org/10.1016/j.lfs.2005.09.043
Abstract
No abstract availableKeywords
This publication has 33 references indexed in Scilit:
- NEUROPHARMACOKINETICS OF A NEW α-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLE PROPIONIC ACID (AMPA) MODULATOR, S18986 [(S)-2,3-DIHYDRO-[3,4]CYCLOPENTANO-1,2,4-BENZOTHIADIAZINE-1,1-DIOXIDE], IN THE RATPublished by American Society for Pharmacology & Experimental Therapeutics (ASPET) ,2005
- Multidrug Resistance Protein (MRP) 4- and MRP 5-Mediated Efflux of 9-(2-Phosphonylmethoxyethyl)adenine by MicrogliaJournal of Pharmacology and Experimental Therapeutics, 2004
- Evidence for an active transport of morphine‐6‐β‐d‐glucuronide but not P‐glycoprotein‐mediated at the blood–brain barrierJournal of Neurochemistry, 2003
- Functional Expression of the Multidrug Resistance Protein 1 in MicrogliaJournal of Pharmacology and Experimental Therapeutics, 2003
- Screening of multidrug-resistance sensitive drugs by in situ brain perfusion in P-glycoprotein-deficient mice.Pharmaceutical Research, 2001
- Human Neurons Express the Polyspecific Cation Transporter hOCT2, Which Translocates Monoamine Neurotransmitters, Amantadine, and MemantinePublished by American Society for Pharmacology & Experimental Therapeutics (ASPET) ,1998
- Morphine and morphine metabolite kinetics in the rat brain as assessed by transcortical microdialysisLife Sciences, 1994
- Steady-state theory for quantitative microdialysis of solutes and water in vivo and in vitroLife Sciences, 1990
- Morphine-6-glucuronide: Analgesic effects and receptor binding profile in ratsLife Sciences, 1988
- Morphine‐6‐glucuronide Has High Affinity for the Opioid ReceptorBasic & Clinical Pharmacology & Toxicology, 1987