Marine actinomycetes as a source of novel secondary metabolites
- 1 January 2005
- journal article
- Published by Springer Science and Business Media LLC in Antonie van Leeuwenhoek
- Vol. 87 (1), 37-42
- https://doi.org/10.1007/s10482-004-6538-8
Abstract
A set of 600 actinomycetes strains which were isolated from marine sediments from various sites in the Pacific and Atlantic Oceans were screened for the production of bioactive secondary metabolites. Marine streptomycete strains were found to be producers of well known chemically diverse antibiotics isolated from terrestrial streptomycetes, as in the case of marine Micromonospora strains. New marine members of the rare genus Verrucosispora seem to be a promising source for novel bioactive secondary metabolites as shown in the case of the abyssomicin producing strain AB-18-032.Keywords
This publication has 22 references indexed in Scilit:
- Abyssomicin C—A Polycyclic Antibiotic from a Marine Verrucosispora Strain as an Inhibitor of the p‐Aminobenzoic Acid/Tetrahydrofolate Biosynthesis PathwayAngewandte Chemie-International Edition, 2004
- Marine natural productsNatural Product Reports, 2004
- Salinosporamide A: A Highly Cytotoxic Proteasome Inhibitor from a Novel Microbial Source, a Marine Bacterium of the New Genus SalinosporaAngewandte Chemie-International Edition, 2003
- Ripromycin and Other Polycyclic Macrolactams from Streptomyces sp. Tue 6239: Taxonomy, Fermentation, Isolation and Biological PropertiesThe Journal of Antibiotics, 2003
- Marine natural productsNatural Product Reports, 2002
- Dereplication for biotechnology screening: PyMS analysis and PCR–RFLP–SSCP (PRS) profiling of 16S rRNA genes of marine and terrestrial actinomycetesApplied Microbiology and Biotechnology, 2002
- Highlights of marine natural products chemistry (1972–1999)Natural Product Reports, 2000
- Marine pharmacologyAntonie van Leeuwenhoek, 2000
- Taxonomy and biotransformation activities of some deep-sea actinomycetesExtremophiles, 1998
- Biosynthetic Capacities of Actinomycetes. 1 Screening for Secondary Metabolites by HPLC and UV-Visible Absorbance Spectral LibrariesNatural Product Letters, 1993