Activation of FGF Receptors is a new Mechanism by which Strontium Ranelate Induces Osteoblastic Cell Growth
- 1 January 2011
- journal article
- Published by S. Karger AG in Cellular Physiology and Biochemistry
- Vol. 27 (3-4), 243-250
- https://doi.org/10.1159/000327950
Abstract
Strontium ranelate (SrRan) is an anti-osteoporotic treatment that reduces the risk of vertebral and hip fractures. Recent in vitro studies suggest that the effect of strontium ranelate on osteoblastic cell growth likely involves two processes including activation of the calcium sensing receptor (CaSR) and a yet undefined mechanism. In the present study, we investigated the CaSR-independent molecular mechanism by which SrRan stimulates osteoblast growthKeywords
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