Time Factors in Interhemispheric Transfer of Learning

Abstract

Single-trial interhemispheric transfer of a discrimination task engram was studied by eliciting spreading depression unilaterally during acquisition of the discrimination. Complete transfer to the untrained side occurred after one trial with both hemispheres functional, if 10 minutes elapsed between this trial and the elicitation of spreading depression in the trained side. If depression was elicited 15 seconds after the trial no transfer occurred. correct response highly probable.