uPA, uPAR, PAI-I: Key intersection of proteolytic, adhesive and chemotacfic highways?
- 1 September 1997
- journal article
- review article
- Published by Elsevier BV in Immunology Today
- Vol. 18 (9), 415-417
- https://doi.org/10.1016/s0167-5699(97)01121-3
Abstract
Through multiple interactions, the unpkinase plasminogen in tivator (uPA) system forms n self-regulated, surface-located, functionally important chemokine. This article examines new data in the field.Keywords
This publication has 23 references indexed in Scilit:
- Phosphorylation of Human Pro-Urokinase on Ser138/303 Impairs Its Receptor-dependent Ability to Promote Myelomonocytic Adherence and MotilityThe Journal of cell biology, 1997
- Plasminogen Activator Inhibitor-1 Represses Integrin- and Vitronectin-Mediated Cell Migration Independently of Its Function as an Inhibitor of Plasminogen ActivationExperimental Cell Research, 1997
- Cell‐Surface Acceleration of Urokinase‐Catalyzed Receptor CleavageEuropean Journal of Biochemistry, 1997
- Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?The Journal of cell biology, 1996
- Regulation of Integrin Function by the Urokinase ReceptorScience, 1996
- The Urokinase Receptor Is a Major Vitronectin-Binding Protein on Endothelial CellsExperimental Cell Research, 1996
- alpha-2 Macroglobulin receptor/Ldl receptor-related protein(Lrp)-dependent internalization of the urokinase receptor.The Journal of cell biology, 1995
- A cleaved form of the receptor for urokinase‐type plasminogen activator in invasive transplanted human and murine tumorsInternational Journal of Cancer, 1994
- Activation of pro-urokinase and plasminogen on human sarcoma cells: a proteolytic system with surface-bound reactants.The Journal of cell biology, 1989
- Urokinase-type plasminogen activator: proenzyme, receptor, and inhibitorsThe Journal of cell biology, 1987