A multi‐intervention approach on drug therapy can lead to a more appropriate drug use in the elderly. LIMM‐Landskrona Integrated Medicines Management
- 23 July 2009
- journal article
- Published by Wiley in Journal of Evaluation in Clinical Practice
- Vol. 15 (4), 660-667
- https://doi.org/10.1111/j.1365-2753.2008.01080.x
Abstract
To evaluate if an integrated medicines management can lead to a more appropriate drug use in elderly inpatients.The study was an intervention study at a department of internal medicine in southern Sweden. During the intervention period pharmacists took part in the daily work at the wards. Systematic interventions aiming to identify, solve and prevent drug-related problems (DRPs) were performed during the patient's hospital stay by multidisciplinary teams consisting of physicians, nurses and pharmacists. DRPs identified by the pharmacist were put forward to the care team and discussed. Medication Appropriateness Index (MAI) was used to evaluate the appropriateness in the patients' drug treatment at admission, discharge and 2 weeks after discharge. In total 43 patients were included, 28 patients in the intervention group and 25 patients in the group which was used as control.For the intervention group there was a significant decrease in the number of inappropriate drugs compared with the control group (P = 0.049). Indication, duration and expenses were the MAI-dimensions with most inappropriate ratings, and the drugs with most inappropriate ratings were anxiolytics, hypnotics and sedatives.This kind of systematic approach on drug therapy can result in a more appropriate drug use in the elderly.Keywords
This publication has 27 references indexed in Scilit:
- Polypharmacy and Prescribing Quality in Older PeopleJournal of the American Geriatrics Society, 2006
- Inappropriate Medication Use Among Frail Elderly InpatientsAnnals of Pharmacotherapy, 2004
- Adverse drug reactions as a cause for admissions to a department of internal medicinePharmacoepidemiology and Drug Safety, 2002
- Quality of Drug Use in Swedish Nursing HomesClinical Drug Investigation, 2000
- Incidence of Adverse Drug Reactions in Hospitalized PatientsJAMA, 1998
- Appropriateness of Medication Prescribing in Ambulatory Elderly PatientsJournal of the American Geriatrics Society, 1994
- A summated score for the medication appropriateness index: development and assessment of clinimetric properties including content validityJournal of Clinical Epidemiology, 1994
- Drug-Related Hospital AdmissionsAnnals of Pharmacotherapy, 1993
- A method for assessing drug therapy appropriatenessJournal of Clinical Epidemiology, 1992
- Drug-related problems causing admission to a medical clinicEuropean Journal of Clinical Pharmacology, 1981