Value of the Modified Hodge Test for Detection of Emerging Carbapenemases in Enterobacteriaceae

Abstract
The modified Hodge test has an excellent sensitivity for detecting enterobacterial isolates producing Ambler class A (KPC) and class D (OXA-48) carbapenemases. Its sensitivity is low for NDM-1 producers (50%) but is increased to 85.7% by adding ZnSO 4 (100 μg/ml) in the culture medium. However, this test has a low specificity and is time-consuming.