Grignard Reactions in Imidazolium Ionic Liquids
- 12 May 2006
- journal article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 71 (12), 4659-4662
- https://doi.org/10.1021/jo060536o
Abstract
A new, base-stable, imidazolium room-temperature ionic liquid (RTIL) has been prepared and applied to the addition of Grignard reagents to carbonyl compounds. These reactions occur readily at ambient temperature to afford the alcohol products in good to excellent yield. The RTIL can be recycled and reused numerous times without any difficulty.Keywords
This publication has 8 references indexed in Scilit:
- An imidazolinium salt as ionic liquid for medium and strong basesGreen Chemistry, 2005
- Preparation and Regioselective SN2‘ Reaction of Novel gem-Difluorinated Vinyloxiranes with RLiThe Journal of Organic Chemistry, 2004
- Properties of ionic liquid solvents for catalysisJournal of Molecular Catalysis A: Chemical, 2004
- Pentadienyl transfer reagents based on zirconium: preparation and reactions with carbonyl compoundsTetrahedron, 2004
- Synthesis of N-Alkylated derivatives of imidazole as antibacterial agentsBioorganic & Medicinal Chemistry Letters, 2003
- Ionic Liquids—New “Solutions” for Transition Metal CatalysisAngewandte Chemie, 2000
- Room-Temperature Ionic Liquids. Solvents for Synthesis and CatalysisChemical Reviews, 1999
- Hydrogenation and dehydrogenation reactions of phenalenones and dihydrophenalenonesThe Journal of Organic Chemistry, 1992