Introduction and recommendations: working group on indoor air and other complex mixtures.
Open Access
- 1 December 1993
- journal article
- Published by Environmental Health Perspectives in Environmental Health Perspectives
- Vol. 101 (suppl 4), 143-147
- https://doi.org/10.1289/ehp.93101s4143
Abstract
Air in indoor and outdoor environments typically contains many gaseous and particulate pollutants that may affect adversely any individual at sufficiently high concentrations and more sensitive individuals at lower concentrations. The public health relevance of addressing the effects of mixtures is becoming increasingly evident as we improve the concept of total personal exposure to pollution and obtain more data from personal monitoring. The papers within this volume represent the deliberations of a working group assembled with the goal of improving the epidemiologic approach to investigating the health effects of indoor air pollution and other complex mixtures. The group, composed of epidemiologists, human and animal toxicologists, and experts on biomarkers, comprehensively reviewed the methodologic issues involved in investigating complex mixtures. Members noted the deficiencies of current epidemiologic methodology for studying complex mixtures and called for broad-based advances in study design, exposure assessment, outcome assessment, and data analysis and interpretation. Understanding the health effects of complex mixtures will require multidisciplinary research using not only epidemiologic studies incorporating the new methods of exposure assessment but animal and clinical toxicology.Keywords
This publication has 17 references indexed in Scilit:
- Toxicological approaches to complex mixtures.Environmental Health Perspectives, 1993
- Assessing exposures to inhaled complex mixtures.Environmental Health Perspectives, 1993
- Basic problems in interaction assessment.Environmental Health Perspectives, 1993
- Utility of controlled human exposure studies for assessing the health effects of complex mixtures and indoor air pollutants.Environmental Health Perspectives, 1993
- Biological markers of intermediate outcomes in studies of indoor air and other complex mixtures.Environmental Health Perspectives, 1993
- Epidemiologic study design for investigating respiratory health effects of complex air pollution mixtures.Environmental Health Perspectives, 1993
- Epidemiological studies of neurotoxic, reproductive, and carcinogenic effects of complex mixtures.Environmental Health Perspectives, 1993
- Complex mixtures and indoor air pollution: overview of epidemiologic methods.Environmental Health Perspectives, 1993
- Assessment of health effects in epidemiologic studies of air pollution.Environmental Health Perspectives, 1993
- Acid air and healthEnvironmental Science & Technology, 1990