Phosphotyrosines 627 and 659 of Gab1 Constitute a Bisphosphoryl Tyrosine-based Activation Motif (BTAM) Conferring Binding and Activation of SHP2
Open Access
- 1 June 2001
- journal article
- Published by Elsevier BV
- Vol. 276 (26), 24380-24387
- https://doi.org/10.1074/jbc.m010275200
Abstract
No abstract availableKeywords
This publication has 30 references indexed in Scilit:
- Requirement of SHP2 Binding to Grb2-associated Binder-1 for Mitogen-activated Protein Kinase Activation in Response to Lysophosphatidic Acid and Epidermal Growth FactorPublished by Elsevier BV ,2000
- Signaling of Hepatocyte Growth Factor/Scatter Factor (HGF) to the Small GTPase Rap1 via the Large Docking Protein Gab1 and the Adapter Protein CRKLPublished by Elsevier BV ,2000
- Shp-2 Tyrosine Phosphatase: Signaling One Cell or ManyExperimental Cell Research, 1999
- A Common Requirement for the Catalytic Activity and Both SH2 Domains of SHP-2 in Mitogen-activated Protein (MAP) Kinase Activation by the ErbB Family of ReceptorsPublished by Elsevier BV ,1998
- The Shp-2 Tyrosine Phosphatase Has Opposite Effects in Mediating the Activation of Extracellular Signal-regulated and c-Jun NH2-terminal Mitogen-activated Protein KinasesPublished by Elsevier BV ,1998
- Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesisNature, 1996
- Activation of Protein-tyrosine Phosphatase SH-PTP2 by a Tyrosine-based Activation Motif of a Novel Brain MoleculePublished by Elsevier BV ,1996
- A Grb2-associated docking protein in EGF- and insulin-receptor signallingNature, 1996
- Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2Nature, 1996
- Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunitsNature, 1994