Global left-ventricular function by tissue Doppler imaging in pediatric dialysis patients
- 1 May 2008
- journal article
- research article
- Published by Springer Science and Business Media LLC in Pediatric Nephrology
- Vol. 23 (5), 779-785
- https://doi.org/10.1007/s00467-007-0734-5
Abstract
Cardiovascular abnormalities are observed in most children with end-stage renal disease (ESRD). The aim of this study was evaluation of left-ventricular (LV) myocardial performance using tissue-Doppler imaging (TDI) in patients with ESRD. Twenty-five patients with ESRD and 25 healthy gender- and age-matched control subjects were assessed with conventional M-mode echocardiography, pulsed-wave Doppler (PWD), and TDI. Myocardial Performance Index (MPI) and LV mass index (LVMI) were calculated. MPI and conventional echo-Doppler indices were compared in the ESRD and control groups. Significant differences were present in the mean systolic and diastolic blood pressure (BP) between children with ESRD and healthy children (p = 0.007 and p < 0.001, respectively). The mean LVMI was significantly greater in the patient group (p < 0.001). The tissue-Doppler MPI of patients was significantly higher than that in healthy children (p < 0.001). LVMI was significantly correlated with systolic and diastolic BP. MPI obtained by TDI was significantly correlated with LVMI. Our study confirms that LV dysfunction is present in patients with ESRD and hypertension is an important risk factor.Keywords
This publication has 35 references indexed in Scilit:
- Reduced Systolic Myocardial Function in Children with Chronic Renal InsufficiencyJournal of the American Society of Nephrology, 2007
- Evaluation of cardiac global function using the myocardial performance index by tissue Doppler echocardiography in patients with uremia.Journal of Ultrasound in Medicine, 2006
- Disagreement between tissue Doppler imaging and conventional pulsed wave Doppler in the measurement of myocardial performance indexEuropean Heart Journal - Cardiovascular Imaging, 2006
- Severe cardiac hypertrophy and long-term dialysis: the Midwest Pediatric Nephrolgy Consortium studyPediatric Nephrology, 2006
- Abnormal cardiac function in children after renal transplantationAmerican Journal of Kidney Diseases, 2004
- Impaired left ventricular diastolic function in children with chronic renal failureKidney International, 2004
- Cardiac disease in young adult patients with end-stage renal disease since childhood: A Dutch cohort studyKidney International, 2003
- Severe left ventricular hypertrophy in pediatric dialysis: prevalence and predictorsPediatric Nephrology, 2000
- Noninvasive Doppler-derived myocardial performance index: Correlation with simultaneous measurements of cardiac catheterization measurementsJournal of the American Society of Echocardiography, 1997
- Left ventricular abnormalities in children, adolescents and young adults with renal diseaseKidney International, 1996