EEG and cardiac activation during periodic leg movements in sleep
- 1 March 1999
- journal article
- Published by Ovid Technologies (Wolters Kluwer Health) in Neurology
- Vol. 52 (4), 786
- https://doi.org/10.1212/wnl.52.4.786
Abstract
Objective: To investigate other physiologic changes that occur with periodic leg movements during sleep (PLMS) that might be considered to be more sensitive indices of sleep fragmentation. Background: Although PLMS are associated with recurrent microarousals (MA), the frequency of PLMS with MA does not correlate with objective daytime sleepiness. It is postulated that the lack of correlation results from the low sensitivity of the standard criteria used to score MA. Methods: Ten drug-free patients with a polygraphic and clinical diagnosis of restless legs syndrome (RLS) and PLMS were examined. The EEG correlates of PLMS were analyzed by visual scoring and spectral analysis during PLMS that ended in a visible microarousal (PLMS with MA) or not (PLMS without MA). The R-R interval in the EKG signal was also examined. Results: A total of 34% of PLMS were associated with MA lasting >3 seconds, and 3% of PLMS were associated with MA lasting Conclusions: First, visual scoring of MA that include a duration of less than 3 seconds has little effect on the detection of PLMS with MA. Second, EEG activation and tachycardia are present during both types of PLMS. Third, a hierarchy in the arousal response is present—going from autonomic activation to bursts of delta activity to alpha activity to a full awakening.Keywords
This publication has 22 references indexed in Scilit:
- Arterial Blood Pressure Response to Transient Arousals From NREM Sleep in Nonapneic Snorers With Sleep FragmentationChest, 1998
- The effect of nonvisible sleep fragmentation on daytime function.American Journal of Respiratory and Critical Care Medicine, 1997
- Clinical, polysomnographic, and genetic characteristics of restless legs syndrome: A study of 133 patients diagnosed with new standard criteriaMovement Disorders, 1997
- Measurements by biphasic changes of the alpha band amplitude as indicators of arousal levelInternational Journal of Psychophysiology, 1996
- Toward a better definition of the restless legs syndromeMovement Disorders, 1995
- Arousal responses from apneic events during non-rapid-eye-movement sleep.American Journal of Respiratory and Critical Care Medicine, 1995
- Arousal Fluctuations in Non-Rapid Eye Movement ParasomniasJournal Of Clinical Neurophysiology, 1995
- Arousals without awakening—Dynamic aspect of sleepPhysiology & Behavior, 1993
- Auditory Awakening Thresholds in Rem and Nrem Sleep StagesPerceptual and Motor Skills, 1966
- Responses to auditory stimulation, sleep loss and the EEG stages of sleepElectroencephalography and Clinical Neurophysiology, 1964