Supplementary Materials from Early Detection of Ovarian Cancer using the Risk of Ovarian Cancer Algorithm with Frequent CA125 Testing in Women at Increased Familial Risk – Combined Results from Two Screening Trials

Abstract
Supplementary Materials describing "Inclusion and Exclusion Criteria" for the two studies, a detailed description of the "ROCA methods", "Sample Handling and CA125 Assay Instrumentation", and derivation of standards for "Specificity and Positive Predictive Values" for a cohort of women at increased risk.