Oat cell carcinoma, phaeochromocytoma and carcinoid tumours—multiple apud cell neoplasia—A case report
- 1 June 1980
- journal article
- case report
- Published by Wiley in The Journal of Pathology
- Vol. 131 (2), 107-115
- https://doi.org/10.1002/path.1711310203
Abstract
A case of non-familial multiple APUD cell neoplasia is described in which an oat cell carcinoma occurred in association with a phaeochromocytoma and two gastric carcinoids. This is the first reported case in which an oat cell carcinoma has formed part of such a syndrome. The arguments for and against this being a chance association are briefly stated and it is suggested that this case provides some support for the view that oat cell carcinomas are themselves derived from APUD cells. The same patient had autoimmune disease, and although this may be purely fortuitous, a speculative hypothesis is advanced suggesting that the deranged anterior pituitary trophic function seen in Hashimoto's thyroiditis may have predisposed to multiple endocrine neoplasia in this case.Keywords
This publication has 16 references indexed in Scilit:
- Unifying concept of non-pituitary acth-secreting tumors.Evidence of common origin of neural-crest tumors, carcinoids, and oat-cell carcinomasCancer, 1978
- Comparative epidemiology of carcinoid and oat-cell tumors of the lungCancer, 1977
- Peptides in brain and intestineNature, 1976
- Bronchial adenoma: review of 18-year experience at the Brompton Hospital.Thorax, 1976
- A review of 17 cases of carcinoma of the thyroid and phaeochromocytomaJournal of Clinical Pathology, 1965
- The association of pheochromocytoma with carcinoma of the thyroid glandAmerican Journal Of Medicine, 1961
- Tumours of the Lung and the Carcinoid SyndromeThorax, 1960
- Oat‐cell carcinoma of the bronchusThe Journal of Pathology and Bacteriology, 1959
- Histopathology of pheochromocytomaCancer, 1959
- Genetic aspects of adenomatosis of endocrine glandsAmerican Journal Of Medicine, 1954