Diagnosis and Treatment of Vulvar Lichen Sclerosus: An Update for Dermatologists
- 9 July 2018
- journal article
- review article
- Published by Springer Science and Business Media LLC in American Journal of Clinical Dermatology
- Vol. 19 (5), 695-706
- https://doi.org/10.1007/s40257-018-0364-7
Abstract
Vulvar lichen sclerosus is an important skin disease that is common in women in their 50 s and beyond; however, it can also affect females of any age, including children. If not treated, it has the potential to cause significant and permanent scarring and deformity of the vulvar structure. In addition, if untreated, it is associated with a 2–6% lifetime risk of malignant squamous neoplasia of the vulva. Lichen sclerosus has been considered a difficult to manage condition; however, both serious complications can potentially be prevented with early intervention with topical corticosteroid, suggesting that the course of the disease can be treatment modified.Keywords
This publication has 63 references indexed in Scilit:
- The effect of vulvar lichen sclerosus on quality of life and sexual functioningJournal of Psychosomatic Obstetrics & Gynecology, 2010
- The high rate of familial lichen sclerosus suggests a genetic contribution: an observational cohort studyJournal of the European Academy of Dermatology and Venereology, 2010
- Long‐term management of vulval lichen sclerosus in adult womenAustralian and New Zealand Journal of Obstetrics and Gynaecology, 2010
- Paediatric vulval lichen sclerosusAustralasian Journal of Dermatology, 2009
- Gender and age prevalence distributions of morphea en plaque and anogenital lichen sclerosusJournal of the European Academy of Dermatology and Venereology, 2007
- Clinical review of 202 patients with vulval lichen sclerosus: A possible association with psoriasisAustralasian Journal of Dermatology, 2007
- The Association Between HLA DR, DQ Antigens, and Vulval Lichen Sclerosus in the UK: HLA DRB1*12 and its Associated DRB1*12/DQB1*0301/04/09/010 Haplotype Confers Susceptibility to Vulval Lichen Sclerosus, and HLA DRB1*0301/04 and its Associated DRB1*0301/04/DQB1*0201/02/03 Haplotype Protects from Vulval Lichen SclerosusJournal of Investigative Dermatology, 2005
- Lichen sclerosusClinical and Experimental Dermatology, 2003
- Genital lichen sclerosus associated with incontinenceJournal of Obstetrics and Gynaecology, 2002
- Topical testosterone in the treatment of vulvar lichen sclerosusInternational Journal of Gynecology & Obstetrics, 1994