Hemorrhagic Moyamoya Disease in Children
- 1 January 2016
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Stroke
- Vol. 47 (1), 240-243
- https://doi.org/10.1161/strokeaha.115.010512
Abstract
Background and Purpose—: Here, we describe the clinical, angiographic characteristics, and long-term surgical outcome of hemorrhagic moyamoya disease in children. Methods—: We retrospectively collected 374 consecutive children with moyamoya disease (hemorrhagic 30 and ischemic 344) between 2004 and 2012 in our hospital. The clinical and radiological characteristics of the hemorrhagic patients were retrospectively described and analyzed. All the hemorrhagic patients underwent encephalo-duro-arterio-synangiosis procedure. Digital subtraction angiography was performed to evaluate the efficacy of vascularization. Clinical follow-up outcomes were obtained through clinical visits, telephone, or letter interview. Results—: In our study, the ratio of female to male patients in the hemorrhagic group was significantly higher than the ischemic group (2:1 versus 0.9:1; P P <0.05). Good or fair vascularization were observed in all the 15 children with digital subtraction angiography follow-up. Clinical outcomes showed that 25 of 30 (83%) patients had no disability (modified Rankin scale score, 0 and 1); 1 patient (3.3%) died of recurrent hemorrhagic stroke. Conclusions—: The presence of anterior choroidal artery and posterior communicating artery dilation may be associated with the bleeding episode in the children with hemorrhagic moyamoya disease. The encephalo-duro-arterio-synangiosis surgery can effectively increase the cerebral blood flow in children, which may decrease the incidence of recurrent hemorrhage.Keywords
This publication has 9 references indexed in Scilit:
- Epidemiological and Clinical Features of Moyamoya Disease in the USANeuroepidemiology, 2013
- Long term outcome after conservative and surgical treatment of haemorrhagic moyamoya diseaseJournal of Neurology, Neurosurgery & Psychiatry, 2012
- Moyamoya Disease in ChinaStroke, 2012
- Hemorrhagic moyamoya disease in children: clinical features and surgical outcomeChild's Nervous System, 2011
- Evaluation of angiographic changes of the anterior choroidal and posterior communicating arteries for predicting cerebrovascular lesions in adult moyamoya diseaseJournal of Clinical Neuroscience, 2011
- Angiographic Dilatation and Branch Extension of the Anterior Choroidal and Posterior Communicating Arteries Are Predictors of Hemorrhage in Adult Moyamoya PatientsStroke, 2003
- Guidelines for the diagnosis and treatment of spontaneous occlusion of the circle of Willis (`Moyamoya' disease)Clinical Neurology and Neurosurgery, 1997
- Surgical Treatment of Moyamoya Disease in Pediatric Patients–Comparison between the Results of Indirect and Direct Revascularization ProceduresNeurosurgery, 1992
- Cerebrovascular "Moyamoya" DiseaseArchives of Neurology, 1969