Gardner's syndrome associated fibromas
- 1 July 2004
- journal article
- Published by Wiley in Pathology International
- Vol. 54 (7), 523-526
- https://doi.org/10.1111/j.1440-1827.2004.01660.x
Abstract
Three patients with Gardner's syndrome having benign fibrous proliferations in the soft tissues and the oral cavity are presented. Lesions in all three patients were morphologically different. Two excised lesions in Case 1 were histologically identical to nuchal-type fibroma (NTF) and one lesion in this patient was an epidermal cyst. Case 2 had a lesion located in the soft tissues of the shoulder, which was morphologically similar to NTF and, in addition, contained mildly atypical and multinucleated fibroblastic cells. The oral lesion in Case 3 looked like a fibroma and was morphologically different from all fibrous lesions that have ever been described in Gardner's syndrome. The cases in the present report show that the term Gardner's fibroma is just a descriptive name encompassing a spectrum of morphologically different benign fibrous proliferations associated with this syndrome. Therefore, the term Gardner's fibroma should not be used as a specific name for NTF arising in patients with Gardner's syndrome as suggested in the most recent WHO classification of soft tissue and bone tumors.Keywords
This publication has 13 references indexed in Scilit:
- Nuchal-Type Fibroma Is Positive for CD34 and CD99The American Journal of Surgical Pathology, 2001
- Gardner SyndromeThe American Journal of Surgical Pathology, 2001
- Gardner-Associated Fibromas (GAF) in Young PatientsThe American Journal of Surgical Pathology, 2001
- Non-nuchal-type fibroma associated with Gardner's syndrome: A hitherto-unreported mesenchymal tumor different from fibromatosis and nuchal-type fibromaPathology - Research and Practice, 2000
- Nuchal Fibroma should be recognized as a new Extracolonic Manifestation of Gardner‐Variant Familial Adenomatous PolyposisAnz Journal of Surgery, 2000
- Association between thyroid cancer of cribriform variant and familial adenomatous polyposis.Journal of Clinical Pathology, 1996
- Familial adenomatous polyposis associated thyroid carcinoma: a distinct type of follicular cell neoplasmHistopathology, 1994
- Intra-abdominal FibromatosisThe American Journal of Surgical Pathology, 1990
- Hereditary Gastrointestinal Polyposis SyndromesThe American Journal of Surgical Pathology, 1986
- Pilomatricoma-like changes in the epidermal cysts of Gardner's syndromeJournal of the American Academy of Dermatology, 1983