Experimental studies of capsular equator rings of soft latex
- 1 March 2001
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Journal of Cataract & Refractive Surgery
- Vol. 27 (3), 457-462
- https://doi.org/10.1016/s0886-3350(00)00606-4
Abstract
To determine the efficacy of wide equatorial rings of various materials in reducing posterior capsule opacification (PCO) and maintaining the circular contour of the capsular equator in a rabbit model. Laboratory for Intraocular Microsurgery and Implants, Goldschleger Eye Research Institute, Tel-Aviv University, Sheba Medical Center, Tel-Hashomer, Israel. Closed rings made of poly(methyl methacrylate), Teflon(R), polyurethane, and latex were introduced into the capsular bags of rabbit eyes after removal of the lens material. The soft latex rings were deemed the only practical rings for atraumatic implantation through a small incision. Latex rings of 2 dimensions with rectangular edges were implanted in 8 rabbits. One eye served as a control after lens removal and no ring implantation. The eyes were followed for up to 5 months and then evaluated by light microscopy. Posterior capsule opacification was minimal or absent in all animals implanted with the latex rings. Mild to moderate inflammatory reaction was noted in most eyes. It was caused by the ring material or secondary to long-standing pressure on the ciliary tissue. The rings also maintained well the circular contour of the capsular bags. Equatorial rings of soft latex with sharp rectangular edges were effective in minimizing PCO and maintaining the shape of the capsule after lens removal in rabbits. Soft rings made of a biocompatible material may be effective in humans.Keywords
This publication has 10 references indexed in Scilit:
- Preventing posterior capsule opacification by creating a discontinuous sharp bend in the capsuleJournal of Cataract & Refractive Surgery, 1999
- Effect of expandable full-size intraocular lenses on lens centration and capsule opacification in rabbitsJournal of Cataract & Refractive Surgery, 1999
- Posterior capsule opacificationPart 1: Experimental investigationsJournal of Cataract & Refractive Surgery, 1999
- Inhibition of posterior capsule opacification with an immunotoxin specific for lens epithelial cells: 24 month clinical resultsJournal of Cataract & Refractive Surgery, 1998
- Efficacy of Equator Rings in an Experimental Rabbit StudyAmerican Journal of Ophthalmology, 1995
- A ring to support the capsular bag after continuous curvilinear capsulorhexisJournal of Cataract & Refractive Surgery, 1994
- Inhibition of posterior capsule opacification: The effect of colchicine in a sustained drug delivery systemJournal of Cataract & Refractive Surgery, 1993
- Posterior capsule opacificationSurvey of Ophthalmology, 1992
- Inhibition of Posterior Capsule Opacification by 5-Fluorouracil in RabbitsOphthalmic Research, 1990
- Posterior capsular opacification and intraocular lens decentration Part II: Experimental findings on a prototype circular intraocular lens designJournal of Cataract & Refractive Surgery, 1988