Role of autophagy in chemoresistance: Regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA–PKcs and PARP-1
- 29 December 2011
- journal article
- Published by Elsevier BV in Biochemical Pharmacology
- Vol. 83 (6), 747-757
- https://doi.org/10.1016/j.bcp.2011.12.029
Abstract
No abstract availableFunding Information
- Ministry of Education, Science and Technology (R13-2008-010-01001-0)
- National Research Foundation of Korea
This publication has 46 references indexed in Scilit:
- Autophagy Induction by Capsaicin in Malignant Human Breast Cells Is Modulated by p38 and Extracellular Signal-Regulated Mitogen-Activated Protein Kinases and Retards Cell Death by Suppressing Endoplasmic Reticulum Stress-Mediated ApoptosisPublished by American Society for Pharmacology & Experimental Therapeutics (ASPET) ,2010
- ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROSProceedings of the National Academy of Sciences of the United States of America, 2010
- Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasionMolecular Cancer Therapeutics, 2009
- Endoplasmic Reticulum Stress-Mediated Autophagy/Apoptosis Induced by Capsaicin (8-Methyl-N-vanillyl-6-nonenamide) and Dihydrocapsaicin is Regulated by the Extent of c-Jun NH2-Terminal Kinase/Extracellular Signal-Regulated Kinase Activation in WI38 Lung Epithelial Fibroblast CellsThe Journal of pharmacology and experimental therapeutics, 2009
- gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatinNucleic Acids Research, 2008
- p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR SignalingCell, 2008
- Both β‐actin and GAPDH are useful reference genes for normalization of quantitative RT‐PCR in human FFPE tissue samples of prostate cancerThe Prostate, 2008
- p53 modulation of the DNA damage responseJournal of Cellular Biochemistry, 2006
- Autophagy: molecular machinery for self-eatingCell Death & Differentiation, 2005
- Live or let die: the cell's response to p53Nature Reviews Cancer, 2002