Adrenal metastases: CT-guided and MR-thermometry-controlled laser-induced interstitial thermotherapy
- 16 December 2006
- journal article
- Published by Springer Science and Business Media LLC in European Radiology
- Vol. 17 (8), 2020-2027
- https://doi.org/10.1007/s00330-006-0516-7
Abstract
The aim of the study was to evaluate the feasibility, safety and effectiveness of CT-guided and MR-thermometry-controlled laser-induced interstitial thermotherapy (LITT) in adrenal metastases. Nine patients (seven male, two female; average age 65.0 years; range 58.7-75.0 years) with nine unilateral adrenal metastases (mean diameter 4.3 cm) from primaries comprising colorectal carcinoma (n = 5), renal cell carcinoma (n = 1), oesophageal carcinoma (n = 1), carcinoid (n = 1), and hepatocellular carcinoma (n = 1) underwent CT-guided, MR-thermometry-controlled LITT using a 0.5 T MR unit. LITT was performed with an internally irrigated power laser application system with an Nd:YAG laser. A thermosensitive, fast low-angle shot 2D sequence was used for real-time monitoring. Follow-up studies were performed at 24 h and 3 months and, thereafter, at 6-month intervals (median 14 months). All patients tolerated the procedure well under local anaesthesia. No complications occurred. Average number of laser applicators per tumour: 1.9 (range 1-4); mean applied laser energy 33 kJ (range 15.3-94.6 kJ), mean diameter of the laser-induced coagulation necrosis 4.5 cm (range 2.5-7.5 cm). Complete ablation was achieved in seven lesions, verified by MR imaging; progression was detected in two lesions in the follow-up. The preliminary results suggest that CT-guided, MR-thermometry-controlled LITT is a safe, minimally invasive and promising procedure for treating adrenal metastases.This publication has 42 references indexed in Scilit:
- Radiofrequency ablation of adrenal tumors and adrenocortical carcinoma metastasesCancer, 2003
- Laser-Induced Thermotherapy of the Vertebral BodyInvestigative Radiology, 2002
- Percutaneous Ethanol Injection for Treatment of Adrenal Metastasis from Hepatocellular CarcinomaAmerican Journal of Roentgenology, 2000
- Noradrenaline improves the tumour to normal blood flow ratio and drug delivery in a model of liver metastasesBritish Journal of Surgery, 1999
- Characterization of adrenal masses using unenhanced CT: an analysis of the CT literature.American Journal of Roentgenology, 1998
- Transcatheter Arterial Renal and Andrenal Embolization with Iohexol-Ethanol SolutionsInvestigative Radiology, 1996
- Radiofrequency tissue ablation: Increased lesion diameter with a perfusion electrodeAcademic Radiology, 1996
- Radiofrequency tissue ablation: Importance of local temperature along the electrode tip exposure in determining lesion shape and sizeAcademic Radiology, 1996
- Differentiation of adrenal adenomas from nonadenomas using CT attenuation values.American Journal of Roentgenology, 1996
- In vivo MR spectroscopic imaging of the adrenal glands: distinction between adenomas and carcinomas larger than 15 mm based on lipid contentAmerican Journal of Roentgenology, 1989