Association of Age-Related Hearing Loss With Cognitive Function, Cognitive Impairment, and Dementia
Top Cited Papers
Open Access
- 1 February 2018
- journal article
- review article
- Published by American Medical Association (AMA) in JAMA Otolaryngology–Head & Neck Surgery
- Vol. 144 (2), 115-126
- https://doi.org/10.1001/jamaoto.2017.2513
Abstract
Dementia affects an estimated 46.8 million persons worldwide and is projected to affect approximately 131.5 million in 2050 with an estimated cost of US $818 billion in 2015 and US $2 trillion by 2050.1 Current pharmaceutical approaches targeting neuropathologic processes such as Alzheimer disease (AD) offer limited benefit with symptom-modifying effects at best.2 Switching to a preventive strategy through reduction of risk factors may be more beneficial than pharmacologic therapy after clinical expression of neuropathologic changes3 and may lead to significant reductions in medical costs.4Keywords
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