CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016
Top Cited Papers
Open Access
- 19 April 2016
- journal article
- review article
- Published by American Medical Association (AMA) in JAMA
- Vol. 315 (15), 1624-1645
- https://doi.org/10.1001/jama.2016.1464
Abstract
The number of people experiencing chronic pain is substantial, with US prevalence estimated at 11.2% of the adult population.1 Patients should receive appropriate pain treatment based on a careful consideration of the benefits and risks of treatment options. Opioids are commonly prescribed for pain, with approximately 3% to 4% of the adult US population prescribed long-term opioid therapy.2 Evidence supports short-term efficacy of opioids in randomized clinical trials lasting primarily 12 weeks or less,3 and patients receiving opioid therapy for chronic pain report some pain relief when surveyed.4-6 However, few studies have been conducted to rigorously assess the long-term benefits of opioids for chronic pain (pain lasting >3 months) with outcomes examined at least 1 year later.7 Opioid pain medication use presents serious risks. From 1999 to 2014, more than 165 000 persons died of overdose related to opioid pain medication in the United States.8 In 2013 alone, an estimated 1.9 million persons abused or were dependent on prescription opioid pain medication.9 Primary care clinicians report concern about opioid pain medication misuse, find managing patients with chronic pain stressful, express concern about patient addiction, and report insufficient training in prescribing opioids.10Keywords
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