Interrogating domain-domain interactions with parsimony based approaches
Open Access
- 26 March 2008
- journal article
- research article
- Published by Springer Science and Business Media LLC in BMC Bioinformatics
- Vol. 9 (1), 171
- https://doi.org/10.1186/1471-2105-9-171
Abstract
The identification and characterization of interacting domain pairs is an important step towards understanding protein interactions. In the last few years, several methods to predict domain interactions have been proposed. Understanding the power and the limitations of these methods is key to the development of improved approaches and better understanding of the nature of these interactions.Keywords
This publication has 45 references indexed in Scilit:
- Co-evolutionary Analysis of Domains in Interacting Proteins Reveals Insights into Domain–Domain Interactions Mediating Protein–Protein InteractionsJournal of Molecular Biology, 2006
- Global landscape of protein complexes in the yeast Saccharomyces cerevisiaeNature, 2006
- A Map of the Interactome Network of the Metazoan C. elegansScience, 2004
- The Pfam protein families databaseNucleic Acids Research, 2004
- The Database of Interacting Proteins: 2004 updateNucleic Acids Research, 2004
- A Protein Interaction Map of Drosophila melanogasterScience, 2003
- Comparative assessment of large-scale data sets of protein–protein interactionsNature, 2002
- Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometryNature, 2002
- Functional organization of the yeast proteome by systematic analysis of protein complexesNature, 2002
- A comprehensive two-hybrid analysis to explore the yeast protein interactomeProceedings of the National Academy of Sciences, 2001