Neuro-endocrine regulation of blood pressure
Open Access
- 1 January 2011
- journal article
- review article
- Published by Medknow in Indian Journal of Endocrinology and Metabolism
- Vol. 15 (8), 281-8
- https://doi.org/10.4103/2230-8210.86860
Abstract
As our understanding of the underlying aetiology of hypertension is far from adequate, over 90% of patients with hypertension receive a diagnosis of essential hypertension. This non-specific diagnosis leads to suboptimal therapeutics and a major problem with non-compliance. Understanding the normal control of blood pressure (BP) is, hence, important for a better understanding of the disease.This review attempts to unravel the present understanding of BP control. The local mechanisms of BP control, the neural mechanisms, renal-endocrine mechanisms, and a variety of other hormones that have a bearing in normal BP control are discussed and the possible role in the pathophysiology is alluded to.Keywords
This publication has 66 references indexed in Scilit:
- Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and miceJCI Insight, 2009
- Role of Endothelin-1 in Clinical HypertensionHypertension, 2008
- Rationale for use of an exercise end point and design for the ADVANCE (A Dose evaluation of a Vasopressin ANtagonist in CHF patients undergoing Exercise) trialAmerican Heart Journal, 2003
- Pathophysiological role of leptin in obesity-related hypertensionJCI Insight, 2000
- Impaired baroreflex sensitivity and sympathovagal balance in syndrome XThe American Journal of Cardiology, 1998
- Relationship Between Left Ventricular Geometry and Natriuretic Peptide Levels in Essential HypertensionHypertension, 1996
- Immunoreactive adrenomedullin in human plasmaFEBS Letters, 1994
- Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat.Hypertension, 1986
- A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in ratsLife Sciences, 1981
- The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholineNature, 1980