Human Cu/Zn Superoxide Dismutase (SOD1) Overexpression in Mice Causes Mitochondrial Vacuolization, Axonal Degeneration, and Premature Motoneuron Death and Accelerates Motoneuron Disease in Mice Expressing a Familial Amyotrophic Lateral Sclerosis Mutant SOD1
- 1 December 2000
- journal article
- Published by Elsevier BV in Neurobiology of Disease
- Vol. 7 (6), 623-643
- https://doi.org/10.1006/nbdi.2000.0299
Abstract
No abstract availableKeywords
This publication has 61 references indexed in Scilit:
- Overexpression of copper/zinc superoxide dismutase: A novel cause of murine muscular dystrophyAnnals of Neurology, 1998
- Axonal Transport of Mutant Superoxide Dismutase 1 and Focal Axonal Abnormalities in the Proximal Axons of Transgenic MiceNeurobiology of Disease, 1998
- Stability of Mutant Superoxide Dismutase-1 Associated with Familial Amyotrophic Lateral Sclerosis Determines the Manner of Copper Release and Induction of Thioredoxin in ErythrocytesBiochemical and Biophysical Research Communications, 1997
- Do posttranslational modifications of CuZnSOD lead to sporadic amyotrophic lateral sclerosis?Annals of Neurology, 1997
- Induction of c-Jun immunoreactivity in spinal cord and brainstem neurons in a transgenic mouse model for amyotrophic lateral sclerosisNeuroscience Letters, 1996
- Rapid fluorescencein situ hybridization on interphasic nuclei to discriminate between homozygous and heterozygous transgenic miceTransgenic Research, 1996
- SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASESAnnual Review of Biochemistry, 1995
- Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS)Brain Research, 1995
- Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosisNature, 1993
- Down's syndrome: morphological remodelling and increased complexity in the neuromuscular junction of transgenic CuZn-superoxide dismutase miceJournal of Neurocytology, 1991