A method for differentiating cancer prevalence according to health status, exemplified using a population-based sample of Italian colorectal cancer cases
- 10 December 2012
- journal article
- research article
- Published by Informa UK Limited in Acta Oncologica
- Vol. 52 (2), 294-302
- https://doi.org/10.3109/0284186x.2012.743679
Abstract
Cancer prevalence is the proportion of a population diagnosed with cancer. We present a method for differentiating prevalence into the proportions expected to survive without relapse, die of cancer within a year, and die of cancer within 10 years or survive with relapse at the end of the 10th year. Material and methods. The method was applied to samples of colorectal cancer cases, randomly extracted from four Italian cancer registries (CRs). The CRs collected data on treatments, local relapses, distant relapses, and causes of death: 1) over the entire follow-up to 31 December 2007 for 601 cases diagnosed in 2002 (cohort approach); 2) over a single year (2007) for fi ve cohorts of cases defi ned by year of diagnosis (from 1997 to 2001), alive at 1 January 2007 (total 298 cases). The cohorts were combined into a fi ctitious cohort with 10 years survival experience. For each year j after diagnosis the health status of cases alive at the beginning of j was estimated at the end of the 10th year. From these estimates the 10-year colorectal cancer prevalence was differentiated. Results . We estimated: 74.7% alive without relapse or not undergoing treatment at the end of 10 years; 8.1% had died of colorectal cancer within a year; 11.4% had died of colorectal cancer 1 – 10 years after diagnosis or had relapsed or were undergoing treatment at the end of the 10th year; and 5.8% had died of other causes. Conclusions . We have introduced a new method for estimating the healthcare and rehabilitation demands of cancer survivors based on CR data plus treatment and relapse data specifi cally collected for samples of cases archived by CRsKeywords
This publication has 12 references indexed in Scilit:
- New pathways of care for cancer survivors: adding the numbersBritish Journal of Cancer, 2011
- Rare cancers are not so rare: The rare cancer burden in EuropeEuropean Journal Of Cancer, 2011
- Levels of acute health service use among cancer survivors in the United KingdomEuropean Journal Of Cancer, 2011
- Prevalence of patients with colorectal cancer requiring follow-up or active treatmentEuropean Journal Of Cancer, 2009
- The cure of cancer: A European perspectiveEuropean Journal Of Cancer, 2009
- Temporal trends in the proportion cured for cancer of the colon and rectum: A population‐based study using data from the Finnish Cancer RegistryInternational Journal of Cancer, 2007
- Cancer Prevalence Estimates in Italy from 1970 to 2010Tumori Journal, 2007
- Colon cancer prevalence and estimation of differing care needs of colon cancer patientsAnnals Of Oncology, 2004
- Cancer prevalence in European registry areasAnnals of Oncology, 2002
- Mixture models for cancer survival analysis: application to population-based data with covariatesStatistics in Medicine, 1999