Automatic segmentation of the choroid in enhanced depth imaging optical coherence tomography images
Open Access
- 11 February 2013
- journal article
- Published by Optica Publishing Group in Biomedical Optics Express
- Vol. 4 (3), 397-411
- https://doi.org/10.1364/boe.4.000397
Abstract
Enhanced Depth Imaging (EDI) optical coherence tomography (OCT) provides high-definition cross-sectional images of the choroid in vivo, and hence is used in many clinical studies. However, the quantification of the choroid depends on the manual labelings of two boundaries, Bruch’s membrane and the choroidal-scleral interface. This labeling process is tedious and subjective of inter-observer differences, hence, automatic segmentation of the choroid layer is highly desirable. In this paper, we present a fast and accurate algorithm that could segment the choroid automatically. Bruch’s membrane is detected by searching the pixel with the biggest gradient value above the retinal pigment epithelium (RPE) and the choroidal-scleral interface is delineated by finding the shortest path of the graph formed by valley pixels using Dijkstra’s algorithm. The experiments comparing automatic segmentation results with the manual labelings are conducted on 45 EDI-OCT images and the average of Dice’s Coefficient is 90.5%, which shows good consistency of the algorithm with the manual labelings. The processing time for each image is about 1.25 seconds.Keywords
This publication has 26 references indexed in Scilit:
- Choroidal Thickness in Healthy Chinese SubjectsInvestigative Opthalmology & Visual Science, 2011
- Choroidal Thickness in Polypoidal Choroidal Vasculopathy and Exudative Age-related Macular DegenerationOphthalmology, 2011
- Choroidal Thickness in Normal Eyes Measured Using Cirrus HD Optical Coherence TomographyAmerican Journal of Ophthalmology, 2010
- Choroidal Thickness in Healthy Japanese SubjectsInvestigative Opthalmology & Visual Science, 2010
- What's the Choroid Got to Do With Angle Closure?American Journal of Ophthalmology, 2009
- A Pilot Study of Enhanced Depth Imaging Optical Coherence Tomography of the Choroid in Normal EyesAmerican Journal of Ophthalmology, 2009
- Enhanced Depth Imaging Spectral-Domain Optical Coherence TomographyAmerican Journal of Ophthalmology, 2008
- Signal degradation by multiple scattering in optical coherence tomography of dense tissue: a Monte Carlo study towards optical clearing of biotissuesPhysics in Medicine & Biology, 2002
- The Circadian Rhythm in Intraocular Pressure and its Relation to Diurnal Ocular Growth Changes in ChicksExperimental Eye Research, 1998
- Optical Coherence TomographyScience, 1991