Tetracyclic Chromane Derivatives from Rhododendron anthopogonoides
- 29 June 2010
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 73 (7), 1203-1206
- https://doi.org/10.1021/np900543r
Abstract
Four new chromane derivatives, anthopogochromane (1), anthopogochromene A (2), anthopogochromene B (3), and anthopogochromene C (4), and two known compounds, daurichromenic acid (5) and ilicicolinic acid B (6), have been isolated from the Chinese medicinal plant Rhododendron anthopogonoides. The S absolute configuration of the stereogenic carbons in the chromane and chromene rings of 1-4 was determined from their circular dichroism spectra. Compounds 1 and 2 inhibited compound 48/80-induced histamine release from rat peritoneal mast cells.Keywords
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