Caffeine and theophylline analogues: Correlation of behavioral effects with activity as adenosine receptor antagonists and as phosphodiesterase inhibitors
Open Access
- 1 January 1988
- journal article
- research article
- Published by Elsevier BV in Life Sciences
- Vol. 43 (5), 387-398
- https://doi.org/10.1016/0024-3205(88)90517-6
Abstract
No abstract availableThis publication has 18 references indexed in Scilit:
- 3,7-Dimethyl-1-propargylxanthine: A potent and selective in vivo antagonist of adenosine analogsLife Sciences, 1988
- Analogs of caffeine: Antagonists with selectivity for A2 adenosine receptorsLife Sciences, 1986
- Analogs of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptorsJournal of Medicinal Chemistry, 1986
- Assessment of selective inhibition of rat cerebral cortical calcium-independent and calcium-dependent phosphodiesterases in crude extracts using deoxycyclic AMP and potassium ionsBiochimica et Biophysica Acta (BBA) - General Subjects, 1984
- Tracheal relaxant and cardiostimulant actions of xanthines can be differentiated from diuretic and CNS-stimulant effects. Role of adenosine antagonism?Life Sciences, 1982
- Adenosine receptors: targets for future drugsJournal of Medicinal Chemistry, 1982
- The role of adenosine and its nucleotides in central synaptic transmissionProgress in Neurobiology, 1981
- Alkylxanthines: Inhibition of adenosine-elicited accumulation of cyclic AMP in brain slices and of brain phosphodiesterase activityLife Sciences, 1979
- Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reactionBiochemical Pharmacology, 1973
- 8-Substituted theophyllines. In vitro inhibition of 3',5'-cyclic adenosine monophosphate phosphodiesterase and pharmacological spectrum in miceJournal of Medicinal Chemistry, 1971