Lyme disease-associated glomerulonephritis
Open Access
- 12 July 2011
- journal article
- case report
- Published by Oxford University Press (OUP) in Nephrology Dialysis Transplantation
- Vol. 26 (9), 3054-3056
- https://doi.org/10.1093/ndt/gfr335
Abstract
We report two cases of Lyme disease-associated glomerulonephritis. A 57-year-old female presented with rash, volume overload, hypertension and rapidly progressive glomerulonephritis. Biopsy confirmed an immune complex-mediated, membranoproliferative lesion. She was treated successfully with steroids and antibiotics. In a second case, a 40-year-old male, with a previously known microscopic hematuria, presented with rash, arthralgias, new proteinuria and gross hematuria following a tick bite. Biopsy revealed focal proliferative IgA nephropathy. Treatment with steroids and antibiotics resulted in rapid resolution of findings. Acute Lyme disease may contribute to the development of de novo, or activation of previously quiescent, immune-mediated glomerular disease.This publication has 4 references indexed in Scilit:
- Lyme DiseaseClinics in Laboratory Medicine, 2010
- Membranous glomerulonephritis secondary to Borrelia burgdorferi infection presenting as nephrotic syndromeClinical Kidney Journal, 2009
- MPGN secondary to lyme diseaseAmerican Journal of Kidney Diseases, 2004
- Lyme DiseaseClinical Infectious Diseases, 2000