DIETARY, EVOLUTIONARY, ANDMODERNIZINGINFLUENCES ON THEPREVALENCE OFTYPE2 DIABETES
- 1 July 2003
- journal article
- review article
- Published by Annual Reviews in Annual Review of Nutrition
- Vol. 23 (1), 345-377
- https://doi.org/10.1146/annurev.nutr.23.011702.073212
Abstract
▪ Abstract An evolutionary perspective is used to elucidate the etiology of the current epidemic of type 2 diabetes estimated at 151 million people. Our primate legacy, fossil hominid, and hunting-gathering lifestyles selected for adaptive metabolically thrifty genotypes and phenotypes are rendered deleterious through modern lifestyles that increase energy input and reduce output. The processes of modernization or globalization include the availability and abundance of calorically dense/low-fiber/high-glycemic foods and the adoption of sedentary Western lifestyles, leading to obesity among both children and adults in developed and developing countries. These trends are projected to continue for a number of decades.Keywords
This publication has 143 references indexed in Scilit:
- Energetics and optimization of human walking and running: The 2000 Raymond Pearl memorial lectureAmerican Journal of Human Biology, 2002
- Global and societal implications of the diabetes epidemicNature, 2001
- Diabetes: energetics, development and human evolutionMedical Hypotheses, 2001
- Nutritional consequences of a change in diet from native to agricultural fruits for the Samoan fruit batEcography, 2000
- The Non-Thrifty GenotypeCurrent Anthropology, 1996
- The Nutrition Transition in Low-Income Countries: An Emerging CrisisNutrition Reviews, 1994
- Independent effects of obesity and insulin resistance on postprandial thermogenesis in men.JCI Insight, 1992
- The origins of agriculture: Population growth during a period of declining healthPopulation and Environment, 1991
- Paleolithic NutritionNew England Journal of Medicine, 1985
- HLA antigens in four Pacific populations with non-insulin-dependent diabetes mellitusAnnals of Human Biology, 1982