Hierarchical architecture and real structure in a biomimetic nano-composite of fluorapatite with gelatine: a model system for steps in dentino- and osteogenesis?
- 3 August 2005
- journal article
- highlight
- Published by Royal Society of Chemistry (RSC) in Journal of Materials Chemistry
- Vol. 15 (47), 4992-4996
- https://doi.org/10.1039/b504977f
Abstract
The morphogenesis of hierarchically ordered, spherical aggregates of fluorapatite–gelatine-nanocomposites starts with elongated hexagonal prismatic seeds, followed by fractal branchings and the development of growing dumbbell states. The general principles of this dramatic process of self-organisation are not yet known but should be laid out already in the real structure of the central seed (P. Simon, W. Carrillo-Cabrera, P. Formanek, C. Göbel, D. Geiger, R. Ramlau, H. Tlatlik, J. Buder and R. Kniep, J. Mater. Chem., 2004, 14, 2218, ). Here we describe the structure and inner architecture of the fluorapatite composite seeds which consist of self-similar nano-subunits nucleated by gelatine macromelecules. Although grown without any cell activities, the biomimetic composite closely resembles natural biomaterials based on interactions between collagen and apatite.Keywords
This publication has 12 references indexed in Scilit:
- Mesocrystals: Inorganic Superstructures Made by Highly Parallel Crystallization and Controlled AlignmentAngewandte Chemie-International Edition, 2005
- On the real-structure of biomimetically grown hexagonal prismatic seeds of fluorapatite–gelatine-composites: TEM investigations along [001]Journal of Materials Chemistry, 2004
- Higher‐Order Organization by Mesoscale Self‐Assembly and Transformation of Hybrid NanostructuresAngewandte Chemie-International Edition, 2003
- Organic Templates for the Generation of Inorganic MaterialsAngewandte Chemie-International Edition, 2003
- Hierarchical and Self‐Similar Growth of Self‐Assembled CrystalsAngewandte Chemie-International Edition, 2003
- Bio-inspired Materials ChemistryAdvanced Materials, 2002
- Morphogenesis and Structure of Human Teeth in Relation to Biomimetically Grown Fluorapatite−Gelatine CompositesChemistry of Materials, 2001
- The Chemistry of FormAngewandte Chemie-International Edition, 2000
- Biomimetic Morphogenesis of Fluorapatite-Gelatin Composites: Fractal Growth, the Question of Intrinsic Electric Fields, Core/Shell Assemblies, Hollow Spheres and Reorganization of Denatured CollagenEuropean Journal of Inorganic Chemistry, 1999
- Biomimetic Growth and Self‐Assembly of Fluorapatite Aggregates by Diffusion into Denatured Collagen MatricesAngewandte Chemie-International Edition, 1996