BRAIN-ASSOCIATED STEM CELL ANTIGEN: AN ANTIGEN SHARED BY BRAIN AND HEMOPOIETIC STEM CELLS
Open Access
- 1 August 1972
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 136 (2), 369-374
- https://doi.org/10.1084/jem.136.2.369
Abstract
There is an antigen on mouse brain tissue which is shared by the hemopoietic colony-forming unit or stem cell of the mouse. Treatment of bone marrow or fetal liver cells with anti-brain antisera inhibits expression of colony-forming units. The anti-stem cell antibody is not absorbed by thymus cells and thus can be distinguished from the anti-thymocyte antibody which these antisera also contain.Keywords
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