In Vivo Assessment of Lumbar Vertebral Strength in Elderly Women Using Computed Tomography-Based Nonlinear Finite Element Model
- 1 January 2008
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Spine
- Vol. 33 (1), 27-32
- https://doi.org/10.1097/brs.0b013e31815e3993
Abstract
In vivo study of a computed tomography (CT)-based nonlinear finite element model (FEM).To establish an FEM with the optimum element size to assess the vertebral strength by comparing analyzed data with those obtained from mechanical testing in vitro, and then to assess the second lumbar (L2) vertebral strength in vivo.FEM has been reported to predict vertebral strength in vitro, but has not been used clinically.Comparison among the 3 models with a different element size of 1 mm, 2 mm, and 3 mm was performed to determine which model achieved the most accurate prediction. Vertebral strength was assessed in 78 elderly Japanese women using an FEM with the optimum element size.The optimum element size was 2 mm. The L2 vertebral strength obtained with the FEM was 2154 +/- 685 N, and the model could detect preexisting vertebral fracture better than measurement of bone mineral density.The FEM could assess vertebral strength in vivo.Keywords
This publication has 25 references indexed in Scilit:
- Nonlinear Finite Element Model Predicts Vertebral Bone Strength and Fracture SiteSpine, 2006
- Osteoporosis Prevention, Diagnosis, and TherapyJAMA, 2001
- Epidemiology of Spinal OsteoporosisSpine, 1997
- Anteroposterior and lateral spinal DXA for the assessment of vertebral body strength: Comparison with hip and forearm measurementOsteoporosis International, 1996
- Direct and computed tomography thickness measurements of the human, lumbar vertebral shell and endplateBone, 1994
- In-vitro relationships between vertebral body density, size, and compressive strength the elderly thoracolumbar spineClinical Biomechanics, 1994
- Improved assessment of lumbar vertebral body strength using supine lateral dual-energy X-ray absorptiometryJournal of Bone and Mineral Research, 1994
- Biologically meaningful determinants of the in vitro strength of lumbar vertebraeBone, 1991
- Prediction of the compressive strength of human lumbar vertebraeClinical Biomechanics, 1989
- The predictive value of quantitative computed tomography for vertebral body compressive strength and ash densityBone, 1989