Enhanced RAD21 cohesin expression confers poor prognosis and resistance to chemotherapy in high grade luminal, basal and HER2 breast cancers
Open Access
- 21 January 2011
- journal article
- Published by Springer Science and Business Media LLC in Breast Cancer Research
- Vol. 13 (1), R9
- https://doi.org/10.1186/bcr2814
Abstract
RAD21 is a component of the cohesin complex, which is essential for chromosome segregation and error-free DNA repair. We assessed its prognostic and predictive power in a cohort of in situ and invasive breast cancers, and its effect on chemosensitivity in vitro.Keywords
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