Stimulation of Fetal Hemoglobin Synthesis by Erythropoietin in Baboons
- 13 August 1987
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 317 (7), 415-420
- https://doi.org/10.1056/nejm198708133170704
Abstract
Stimulating the production of fetal hemoglobin may benefit patients with sickle cell anemia by inhibiting sickling. We gave pulsed treatments with high doses of recombinant human erythropoietin to baboons in order to test the hypothesis that the resultant rapid erythroid regeneration would stimulate F cells — i.e., cells that contain fetal hemoglobin.This publication has 36 references indexed in Scilit:
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